Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8128585 | 1.00 | KIF11 (0.39) | KIF11PTPN1GRM6MEN1CYP1A2 | |
| SCHEMBL8125242 | 0.92 | NOS1 (0.43) | KIF11PTPN1KMT2ANOS1 | |
| SCHEMBL8125246 | 0.92 | NOS1 (0.43) | KIF11PTPN1KMT2ANOS1 | |
| SCHEMBL7406141 | 0.88 | TPH1 (0.46) | KIF11GRM6MEN1CYP1A2CYP2C9 | |
| SCHEMBL7406145 | 0.88 | TPH1 (0.46) | KIF11GRM6MEN1CYP1A2CYP2C9 | |
| SCHEMBL7408342 | 0.87 | SLC7A11 (0.45) | KIF11MEN1CYP1A2KMT2ASLC7A11 | |
| SCHEMBL7408347 | 0.87 | SLC7A11 (0.45) | KIF11MEN1CYP1A2KMT2ASLC7A11 | |
| SCHEMBL7159040 | 0.86 | SLC7A5 (0.46) | PTPN1ALPIPKMPTGS1XIAP | |
| SCHEMBL8129370 | 0.86 | SLC7A5 (0.46) | PTPN1ALPIPKMPTGS1XIAP | |
| SCHEMBL7159035 | 0.86 | SLC7A5 (0.46) | PTPN1ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1056837-C | 5-arylisoxazol-4-yl-substituted 2-aminocarboxylic acid compounds | LUNDBECK & CO AS H (DK) | 2000-09-27 | — | — | CN | disclosed |
| EP-0994107-A1 | 5-Arylisoxazol-4-yl-substituted 2-amino carboxylic acid compounds | H. LUNDBECK A/S (DK) | 2000-04-19 | — | — | EP | disclosed |
| CN-1136810-A | 5-arylisoxazol-4-yl-substituted 2-aminocarboxylic acid compounds | LUNDBECK & CO AS H (DK) | 1996-11-27 | — | — | CN | disclosed |