Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136574 | 0.82 | LTA4H (0.52) | LTA4HKMT2AHPGDEPHX1EPHX2 | |
| SCHEMBL4414768 | 0.82 | LTA4H (0.52) | LTA4HKMT2AHPGDEPHX1EPHX2 | |
| SCHEMBL6136289 | 0.81 | LTA4H (0.55) | LTA4HKMT2AHPGDEPHX1P2RX7 | |
| SCHEMBL6136293 | 0.81 | LTA4H (0.55) | LTA4HKMT2AHPGDEPHX1P2RX7 | |
| SCHEMBL6136421 | 0.74 | SMN1; SMN2 (0.49) | LTA4HEPHX1RAB9ASMN1; SMN2 | |
| SCHEMBL4424684 | 0.74 | SMN1; SMN2 (0.49) | LTA4HEPHX1RAB9ASMN1; SMN2 | |
| SCHEMBL7882899 | 0.74 | KMT2A (0.53) | KMT2AHPGDEPHX1P2RX7EPHX2 | |
| SCHEMBL15906239 | 0.72 | ALDH1A1 (0.54) | LTA4HKMT2AHPGDEPHX1EPHX2 | |
| SCHEMBL7437533 | 0.72 | HPGD (0.57) | LTA4HKMT2AHPGDEPHX1P2RX7 | |
| SCHEMBL29700260 | 0.71 | MME (0.37) | LTA4HKMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121342-A1 | DIAMINOPROPIONIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021920-A1 | DIAMINOPROPIONIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-04-20 | — | — | WO | disclosed |