Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 5/20 | 0.40 |
| ▸ | FNTB | P49356 | 5/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412598 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7419456 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7419451 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7412595 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7419223 | 0.86 | ITGB3 (0.53) | ITGB3ITGA2BFPR2LMNAHDAC1 | |
| Acetic Acid SCHEMBL7415684 | 0.84 | ITGB3 (0.64) | ITGB3ITGA2BFPR2LMNAFPR1 | |
| SCHEMBL7415603 | 0.79 | ITGB3 (0.72) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7420718 | 0.79 | ITGB3 (0.72) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL8996391 | 0.78 | HDAC1 (0.49) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL27368967 | 0.78 | ITGB3 (0.65) | ITGB3ITGA2BFPR2HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796245-B1 | PROCESS FOR THE PREPARATION OF AMIDINO PHENYL PYRROLIDINE BETA-ALANINE UREA ANALOGS | SEARLE & CO (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5659063-A | AMINE-BLOCKED METHIONINE ANALOG CYCLIZABLE TO A LACTAM IN NONVOLATILE OR NONTOXIC REAGENTS; ANTITHROMBOTIC AGENTS | G. D. SEARLE & CO. (US) | 1997-08-19 | — | — | US | disclosed |
| US-5610296-A | CHEMICAL INTERMEDIATES OF ANTITHROMBOTICS | G. D. SEARLE & CO. (US) | 1997-03-11 | — | — | US | disclosed |
| WO-1996017827-A1 | PROCESS FOR THE PREPARATION OF AMIDINO PHENYL PYRROLIDINE β-ALANINE UREA ANALOGS | G.D. SEARLE & CO. (US) | 1996-06-13 | — | — | WO | disclosed |
| US-5484946-A | CYCLIZATION AND DEHYDRATION A METHIONINE DERIVATIVE | G. D. SEARLE & CO. (US) | 1996-01-16 | — | — | US | disclosed |