Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753695 | 0.88 | MTNR1A (0.62) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL2284298 | 0.88 | MTNR1A (0.62) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL6133992 | 0.84 | MTNR1A (0.50) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL10144147 | 0.82 | PTGS2 (0.62) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL10364842 | 0.81 | MTNR1A (0.59) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL7410139 | 0.81 | MTNR1A (0.55) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL770327 | 0.79 | MTNR1A (0.58) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL423421 | 0.79 | PTGS2 (0.66) | MTNR1AMTNR1BPTGS2 | |
| SCHEMBL770506 | 0.78 | MTNR1A (0.53) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL21101966 | 0.78 | PTGS2 (0.65) | MTNR1AMTNR1BPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503067-A | HYPOTENSIVE, ANGINA PECTORIS | BOEHRINGER MANNHEIM GMBH (DE) | 1985-03-05 | — | — | US | disclosed |