SCHEMBL770327

SCHEMBL770327

COc1ccccc1SCC[Si](C)(C)C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.58
MTNR1B P49286 1/20 0.58
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
PTGS2 P35354 9/20 0.42
HAO1 Q9UJM8 1/20 0.41
ALDH1A1 P00352 1/20 0.41
ADRA2B P18089 1/20 0.41
PTGS1 P23219 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KMT2A Q03164 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17354071 0.87 MTNR1A (0.56) MTNR1AMTNR1BCA12CA1CA2
SCHEMBL2284298 0.86 MTNR1A (0.62) MTNR1AMTNR1BCA12CA1CA2
SCHEMBL30753695 0.86 MTNR1A (0.62) MTNR1AMTNR1BCA12CA1CA2
SCHEMBL770408 0.83 MTNR1A (0.56) MTNR1AMTNR1BCA12CA1CA2
SCHEMBL10144147 0.81 PTGS2 (0.62) MTNR1AMTNR1BCA12CA1CA2
SCHEMBL7411992 0.79 MTNR1A (0.55) MTNR1AMTNR1BCA12CA1CA2
SCHEMBL10364842 0.79 MTNR1A (0.59) MTNR1AMTNR1BCA12CA1CA2
SCHEMBL7410139 0.79 MTNR1A (0.55) MTNR1AMTNR1BCA12CA1CA2
SCHEMBL16936321 0.79 RAB9A (0.42) MTNR1AMTNR1BALDH1A1KMT2ASMN1; SMN2
SCHEMBL423421 0.78 PTGS2 (0.66) MTNR1AMTNR1BPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9217921-B2 Resist underlayer film forming composition containing silicon having sulfide bond NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-22 US disclosed
US-20120070994-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING SULFIDE BOND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120070994-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING SULFIDE BOND SMC3, SRSF3, SRSF9 MTNR1A 3304/4885MTNR1B 3417/4885CA12 860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.