Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylamine SCHEMBL7408665 | 0.88 | SRC (0.43) | KDM4EPOLBHSD17B10L3MBTL1DYRK1A | |
| SCHEMBL7412394 | 0.88 | SRC (0.43) | KDM4EPOLBHSD17B10L3MBTL1DYRK1A | |
| Bromide SCHEMBL10733467 | 0.86 | SRC (0.42) | KDM4EPOLBHSD17B10L3MBTL1DYRK1A | |
| Water SCHEMBL7408556 | 0.86 | SRC (0.42) | KDM4EPOLBHSD17B10L3MBTL1DYRK1A | |
| SCHEMBL7407905 | 0.83 | KMO (0.39) | KDM4EPOLBHSD17B10L3MBTL1DYRK1A | |
| SCHEMBL10968820 | 0.79 | FABP4 (0.43) | KDM4EPOLBL3MBTL1DYRK1ASRC | |
| Potassium Ion SCHEMBL7409882 | 0.76 | SRC (0.38) | KDM4EPOLBHSD17B10L3MBTL1SRC | |
| SCHEMBL7405683 | 0.76 | KMO (0.45) | KDM4EPOLBHSD17B10L3MBTL1DYRK1A | |
| SCHEMBL7412024 | 0.76 | WEE1 (0.50) | KDM4EPOLBHSD17B10L3MBTL1SRC | |
| Potassium Ion SCHEMBL7415696 | 0.76 | SRC (0.38) | KDM4EPOLBHSD17B10L3MBTL1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631283-A | RENAL VASODILATORS, CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-12-23 | — | — | US | claimed |
| EP-0107398-A1 | Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids | ORTHO PHARMACEUTICAL CORPORATION (US) | 1984-05-02 | — | — | EP | claimed |