Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | CCKAR | P32238 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412095 | 0.89 | HTR6 (0.39) | PTGDR2 | |
| SCHEMBL7405922 | 0.77 | HTR6 (0.36) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL7403922 | 0.74 | SCARB1 (0.48) | DRD2DRD3PTGDR2TBXA2RPTGDR | |
| SCHEMBL7406891 | 0.72 | DRD2 (0.48) | DRD2DRD3L3MBTL1 | |
| SCHEMBL7412556 | 0.72 | DRD2 (0.43) | DRD2DRD3PTGDR2EGFRIGF1R | |
| SCHEMBL7413051 | 0.70 | DRD2 (0.46) | DRD2DRD3PTGDR2KDM4E | |
| SCHEMBL7407733 | 0.70 | DRD2 (0.49) | DRD2DRD3PTGDR2TBXA2RPTGDR | |
| SCHEMBL7408143 | 0.63 | SCARB1 (0.52) | — | |
| SCHEMBL7412976 | 0.63 | DRD2 (0.51) | DRD2DRD3PTGDR2EGFRIGF1R | |
| SCHEMBL7410175 | 0.62 | DRD2 (0.58) | DRD2DRD3PTGDR2TBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |