Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413051 | 0.79 | DRD2 (0.46) | ALDH1A1MCHR1DRD2DRD3 | |
| SCHEMBL7405351 | 0.72 | PTGDR2 (0.43) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL2204301 | 0.65 | MEN1 (0.75) | KMT2AMEN1ALDH1A1SIRT6MAPT | |
| SCHEMBL4191910 | 0.65 | SIRT6 (0.72) | KMT2AMEN1ALDH1A1SIRT6MAPT | |
| SCHEMBL10126930 | 0.63 | WDR5 (0.61) | KMT2AALDH1A1 | |
| SCHEMBL4221243 | 0.63 | KMT2A (0.67) | KMT2AMEN1ALDH1A1SIRT6MAPT | |
| SCHEMBL27178667 | 0.63 | KMT2A (0.60) | KMT2AMEN1SIRT6MAPT | |
| SCHEMBL12431530 | 0.63 | MAPT (0.70) | KMT2AALDH1A1SIRT6MAPTLMNA | |
| SCHEMBL13912 | 0.63 | KMT2A (0.75) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL447471 | 0.63 | SIRT6 (1.00) | KMT2AMEN1ALDH1A1SIRT6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |