Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445322 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10KDM4EMAPT | |
| Water SCHEMBL9830187 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRHSD17B10KDM4EMAPT | |
| Water SCHEMBL9830179 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRHSD17B10KDM4EMAPT | |
| SCHEMBL7409180 | 0.72 | MAPT (0.43) | ALDH1A1HSD17B10KDM4EMAPTLMNA | |
| SCHEMBL7409625 | 0.72 | KMT2A (0.45) | ALDH1A1HSD17B10KDM4EMAPTEGFR | |
| SCHEMBL9831668 | 0.69 | KMT2A (0.40) | ALDH1A1TSHRKDM4EMAPTLMNA | |
| SCHEMBL9832514 | 0.68 | KDM4E (0.42) | ALDH1A1TSHRHSD17B10KDM4EMAPT | |
| SCHEMBL10683659 | 0.66 | HSD17B10 (0.47) | ALDH1A1TSHRHSD17B10KDM4EMAPT | |
| SCHEMBL12325390 | 0.65 | CYP3A4 (0.46) | ALDH1A1TSHRKDM4EMAPTLMNA | |
| SCHEMBL16582707 | 0.65 | SENP7 (0.44) | ALDH1A1HSD17B10KDM4EMAPTSAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843077-A | Isoquinoline derivatives having renal vasodilating properties and/or cardiotonic properties and/or phosphodiesterase inhibiting properties | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-06-27 | — | — | US | disclosed |