Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416288 | 0.91 | MEN1 (0.57) | MEN1KMT2ANPC1PPARGNR1H4 | |
| SCHEMBL8414751 | 0.91 | MEN1 (0.57) | MEN1KMT2ANPC1PPARGNR1H4 | |
| SCHEMBL7416030 | 0.89 | KMT2A (0.50) | MEN1KMT2ANPC1PPARGNR1H4 | |
| SCHEMBL7407208 | 0.83 | NPC1 (0.55) | MEN1KMT2ANPC1PPARGNR1H4 | |
| SCHEMBL7414642 | 0.83 | NPC1 (0.55) | MEN1KMT2ANPC1PPARGNR1H4 | |
| SCHEMBL12700346 | 0.80 | HSD17B10 (0.61) | MEN1KMT2APPARGDHODHPKM | |
| SCHEMBL7409499 | 0.80 | MEN1 (0.61) | MEN1KMT2ANPC1DHODHRAB9A | |
| SCHEMBL7409183 | 0.79 | MEN1 (0.84) | MEN1KMT2ANPC1PKMMAPT | |
| SCHEMBL7410644 | 0.79 | MEN1 (0.84) | MEN1KMT2ANPC1PKMMAPT | |
| SCHEMBL7413373 | 0.78 | CREBBP (0.44) | MEN1KMT2ANPC1PPARGNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999042439-A1 | NOVEL THIOBENZAMIDES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-26 | — | — | WO | claimed |
| WO-1999042439-A1 | NOVEL THIOBENZAMIDES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-26 | — | — | WO | disclosed |
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |