Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416288 | 0.95 | MEN1 (0.57) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL7413259 | 0.91 | MEN1 (0.56) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL7416030 | 0.80 | KMT2A (0.50) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL7410644 | 0.80 | MEN1 (0.84) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL7409183 | 0.80 | MEN1 (0.84) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL7414642 | 0.79 | NPC1 (0.55) | MEN1KMT2ANPC1RAB9APPARG | |
| SCHEMBL7407208 | 0.79 | NPC1 (0.55) | MEN1KMT2ANPC1RAB9APPARG | |
| SCHEMBL7413404 | 0.78 | KMT2A (0.64) | MEN1KMT2ANPC1PPARGMAPT | |
| SCHEMBL8417461 | 0.78 | KMT2A (0.64) | MEN1KMT2ANPC1PPARGMAPT | |
| SCHEMBL7409499 | 0.74 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |