Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416686 | 0.81 | GPR119 (0.46) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7415294 | 0.81 | GPR119 (0.53) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL13335340 | 0.75 | GPR119 (0.70) | GPR119FAAHCHEK2 | |
| SCHEMBL1646632 | 0.74 | GPR119 (0.59) | GPR119SCN9ACHEK2 | |
| SCHEMBL7320461 | 0.73 | GPR119 (0.68) | GPR119FAAHCHEK2 | |
| SCHEMBL7413671 | 0.73 | STS (0.50) | GPR119FAAH | |
| SCHEMBL7318758 | 0.73 | GPR119 (0.74) | GPR119FAAHCHEK2 | |
| SCHEMBL31575002 | 0.73 | GPR119 (0.65) | GPR119FAAH | |
| SCHEMBL1574984 | 0.73 | GPR119 (0.75) | GPR119SCN9ACHEK2 | |
| SCHEMBL1669652 | 0.73 | GPR119 (0.55) | GPR119PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880136-A | PREVENTING THROMBUS FORMATION | MERCK & CO., INC. (US) | 1999-03-09 | — | — | US | disclosed |
| US-5814643-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1998-09-29 | — | — | US | disclosed |