Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | YAP1 | P46937 | 3/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416559 | 0.83 | YAP1 (0.44) | GPR119YAP1ITGB3ITGA2BFAAH | |
| SCHEMBL7413744 | 0.81 | GPR119 (0.54) | GPR119PDE4DFAAHPDE4APDE4B | |
| SCHEMBL7415893 | 0.80 | GPR119 (0.45) | GPR119YAP1ITGB3ITGA2BFAAH | |
| SCHEMBL7987174 | 0.77 | YAP1 (0.53) | YAP1ITGB3ITGA2B | |
| SCHEMBL7987170 | 0.77 | YAP1 (0.53) | YAP1ITGB3ITGA2B | |
| SCHEMBL7413671 | 0.75 | STS (0.50) | GPR119YAP1ITGB3ITGA2BFAAH | |
| SCHEMBL24336797 | 0.73 | YAP1 (0.66) | GPR119YAP1ITGB3ITGA2B | |
| SCHEMBL7986551 | 0.73 | ITGB3 (0.71) | YAP1ITGB3ITGA2B | |
| SCHEMBL7292244 | 0.73 | ITGB3 (0.71) | YAP1ITGB3ITGA2B | |
| SCHEMBL20659982 | 0.73 | KDM4E (0.56) | GPR119YAP1ITGB3ITGA2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880136-A | PREVENTING THROMBUS FORMATION | MERCK & CO., INC. (US) | 1999-03-09 | — | — | US | disclosed |
| US-5814643-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1998-09-29 | — | — | US | disclosed |