Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
| ▸ | YAP1 | P46937 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417403 | 0.96 | STS (0.51) | STSGPR119HTR6TGFBR1YAP1 | |
| SCHEMBL7416512 | 0.93 | STS (0.52) | STSGPR119HTR6TGFBR1YAP1 | |
| SCHEMBL7416856 | 0.88 | GPR119 (0.49) | STSGPR119HTR6TGFBR1FAAH | |
| SCHEMBL7417427 | 0.86 | TGFBR1 (0.52) | GPR119HTR6TGFBR1LIMK2 | |
| SCHEMBL7418854 | 0.86 | GPR119 (0.47) | STSGPR119HTR6TGFBR1YAP1 | |
| SCHEMBL7467827 | 0.85 | GPR119 (0.50) | STSGPR119HTR6TGFBR1 | |
| SCHEMBL7409713 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL7416559 | 0.81 | YAP1 (0.44) | GPR119HTR6YAP1ITGB3ITGA2B | |
| SCHEMBL7413311 | 0.81 | GPR119 (0.46) | GPR119HTR6TGFBR1LIMK2 | |
| SCHEMBL7415441 | 0.81 | GPR119 (0.47) | GPR119HTR6TGFBR1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880136-A | PREVENTING THROMBUS FORMATION | MERCK & CO., INC. (US) | 1999-03-09 | — | — | US | disclosed |
| US-5814643-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1998-09-29 | — | — | US | disclosed |