Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417427 | 0.84 | TGFBR1 (0.52) | GPR119HTR6TGFBR1 | |
| SCHEMBL7416856 | 0.84 | GPR119 (0.49) | GPR119FAAHHTR6TGFBR1SCN9A | |
| SCHEMBL7416559 | 0.82 | YAP1 (0.44) | GPR119FAAHHTR6KDM4EPKM | |
| SCHEMBL7417403 | 0.82 | STS (0.51) | GPR119HTR6KDM4EPKMTGFBR1 | |
| SCHEMBL7415441 | 0.81 | GPR119 (0.47) | GPR119HTR6TGFBR1SCN9A | |
| SCHEMBL7413744 | 0.81 | GPR119 (0.54) | GPR119FAAHPDE4DPDE4APDE4B | |
| SCHEMBL7413311 | 0.80 | GPR119 (0.46) | GPR119HTR6TGFBR1SCN9A | |
| SCHEMBL7413661 | 0.78 | GPR119 (0.57) | GPR119FAAHHTR6KDM4EPKM | |
| SCHEMBL30663176 | 0.78 | GPR119 (0.57) | GPR119FAAHHTR6KDM4EPKM | |
| SCHEMBL26619651 | 0.78 | GPR119 (0.57) | GPR119FAAHHTR6KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880136-A | PREVENTING THROMBUS FORMATION | MERCK & CO., INC. (US) | 1999-03-09 | — | — | US | disclosed |
| US-5814643-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1998-09-29 | — | — | US | disclosed |