Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | TP53 | P04637 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | RB1 | P06400 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410787 | 0.91 | HTR2A (0.47) | HTR6MAPTTP53LMNA | |
| SCHEMBL7402536 | 0.90 | HTR1D (0.57) | HTR6MAPTTP53LMNATHRB | |
| SCHEMBL3800074 | 0.88 | MAPT (0.42) | HTR6MAPTTP53LMNATHRB | |
| SCHEMBL7403630 | 0.88 | CYP19A1 (0.50) | HTR6MAPTTP53RB1 | |
| SCHEMBL7410085 | 0.88 | KMT2A (0.49) | HTR6MAPTTP53LMNAHTR1D | |
| SCHEMBL7407214 | 0.87 | MAPT (0.40) | HTR6MAPTTP53LMNATHRB | |
| SCHEMBL7415797 | 0.81 | CYP2D6 (0.40) | HTR6MAPTTP53LMNAKMT2A | |
| SCHEMBL7463173 | 0.81 | CGAS (0.38) | HTR6MAPTTP53LMNA | |
| SCHEMBL4905222 | 0.76 | VPS4B (0.47) | HTR6MAPTTP53LMNA | |
| SCHEMBL7410694 | 0.75 | HTR6 (0.37) | HTR6TP53RB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |