Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
| ▸ | RB1 | P06400 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415797 | 0.85 | CYP2D6 (0.40) | HTR6CYP19A1CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL7413413 | 0.81 | MCL1 (0.39) | MCL1PARP14 | |
| SCHEMBL7403630 | 0.81 | CYP19A1 (0.50) | HTR6CYP19A1CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7410972 | 0.75 | TRPV1 (0.38) | MCL1PARP14NR2E1HSD17B10RB1 | |
| SCHEMBL7414043 | 0.75 | HTR6 (0.47) | HTR6TP53RB1 | |
| SCHEMBL7463173 | 0.74 | CGAS (0.38) | HTR6CYP2D6CYP1A2PTGS2TP53 | |
| SCHEMBL7413193 | 0.73 | HTR1A (0.44) | HTR6 | |
| SCHEMBL7412807 | 0.73 | CHRNA7 (0.41) | PARP14NR2E1 | |
| SCHEMBL7407214 | 0.71 | MAPT (0.40) | HTR6CYP19A1CYP2D6TP53HPGD | |
| SCHEMBL7410787 | 0.71 | HTR2A (0.47) | HTR6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |