Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | CTSE | P14091 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6374240 | 0.85 | OPRM1 (0.52) | ACEACE2OPRM1CALCRL | |
| SCHEMBL2045662 | 0.83 | REN (0.54) | ACEACE2RENCTSDCTSE | |
| SCHEMBL7419554 | 0.83 | REN (0.54) | ACEACE2RENCTSDCTSE | |
| SCHEMBL8250626 | 0.77 | OPRM1 (0.60) | ACEOPRM1 | |
| SCHEMBL8060131 | 0.77 | ACE (0.56) | ACEACE2REN | |
| SCHEMBL7411063 | 0.77 | ACE (0.56) | ACEACE2REN | |
| SCHEMBL30586507 | 0.77 | SLC6A2 (0.57) | OPRM1RENCALCRL | |
| SCHEMBL30886747 | 0.76 | OPRK1 (0.57) | ACEACE2OPRM1 | |
| SCHEMBL14454334 | 0.76 | NMUR2 (0.63) | OPRM1REN | |
| SCHEMBL10586333 | 0.76 | ACE (0.53) | ACEACE2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000002903-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 2000-01-20 | — | — | WO | disclosed |