Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785294 | 0.80 | MEN1 (0.40) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL8915151 | 0.80 | MEN1 (0.40) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL6871294 | 0.69 | TDP1 (0.41) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL6871290 | 0.69 | TDP1 (0.41) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL1486212 | 0.69 | NAALAD2 (0.44) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL5031613 | 0.69 | NAALAD2 (0.44) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL1401158 | 0.69 | MEN1 (0.44) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL7398552 | 0.68 | DGAT1 (0.44) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL28277578 | 0.68 | MEN1 (0.41) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL28277576 | 0.68 | MEN1 (0.41) | TDP1MEN1GAAKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993006127-A1 | NOVEL AMINO ACID PRODRUG RENIN INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-04-01 | — | — | WO | disclosed |