Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415419 | 0.87 | KDM4E (0.41) | KCNH2ALDH1A1KDM4EGAAGLA | |
| SCHEMBL7410799 | 0.86 | ROCK2 (0.42) | ALDH1A1GAAKMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7406913 | 0.84 | KDM4E (0.43) | ALDH1A1KDM4EGAAMEN1CYP1A2 | |
| SCHEMBL9734334 | 0.74 | NPC1 (0.42) | ALDH1A1MEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL12660672 | 0.69 | KDM4E (0.46) | KCNH2KDM4ECHRNA7HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL11265835 | 0.68 | KDM4E (0.44) | KCNH2ALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL10641597 | 0.65 | KDM4E (0.46) | KCNH2ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL19167806 | 0.65 | KDM4E (0.46) | KCNH2ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL19168622 | 0.64 | MAPT (0.39) | ALDH1A1KMT2ATDP1 | |
| SCHEMBL17500271 | 0.64 | MAPT (0.39) | ALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934319-B1 | 1H-PYRIDO[3,4-b]INDOLE-4-CARBOXAMIDE DERIVATIVES, PREPARATION AND APPLICATION THEREOF IN THERAPEUTICS | SANOFI SYNTHELABO (FR) | 2002-06-05 | — | — | EP | disclosed |
| US-6075021-A | 1H-pyrido[3,4-b]indole-4-carboxamide derivatives, preparation and application thereof in therapeutics | SYNTHELABO (FR) | 2000-06-13 | — | — | US | disclosed |