Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321064 | 0.85 | ALDH1A1 (0.55) | LMNAGAAKMT2AALDH1A1GLA | |
| SCHEMBL31096936 | 0.78 | ALDH1A1 (0.59) | LMNAGAAKMT2AALDH1A1GLA | |
| SCHEMBL27029697 | 0.77 | GAA (0.51) | LMNAGAAKMT2AALDH1A1GLA | |
| SCHEMBL31294122 | 0.74 | KMT2A (0.71) | LMNAGAAKMT2AALDH1A1GLA | |
| SCHEMBL1957529 | 0.74 | HRH3 (0.48) | LMNAGAAKMT2AALDH1A1GLA | |
| SCHEMBL2543543 | 0.74 | PKM (0.56) | FBP1GAAALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL1465414 | 0.73 | LMNA (0.55) | FBP1LMNAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL30986723 | 0.73 | FBP1 (0.59) | FBP1HPGDKMT2AALDH1A1MAPT | |
| SCHEMBL29098408 | 0.73 | HRH3 (0.47) | LMNAGAAKMT2AALDH1A1GLA | |
| SCHEMBL27029786 | 0.73 | GAA (0.47) | LMNAGAAKMT2AALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114035-A1 | QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNTORY LIMITED (JP) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000010982-A1 | QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEROF | SUNTORY LIMITED (JP) | 2000-03-02 | — | — | WO | disclosed |