Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 15/20 | 0.42 |
| ▸ | FPR1 | P21462 | 9/20 | 0.42 |
| ▸ | NPY1R | P25929 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7422393 | 0.95 | ITGB3 (0.46) | ITGB3ITGA2BFPR2FPR1NPY1R | |
| SCHEMBL8116040 | 0.90 | FPR2 (0.47) | ITGB3ITGA2BFPR2FPR1NPY1R | |
| SCHEMBL8117290 | 0.87 | ITGB3 (0.68) | ITGB3ITGA2BFPR2FPR1NPY1R | |
| SCHEMBL8117283 | 0.87 | ITGB3 (0.68) | ITGB3ITGA2BFPR2FPR1NPY1R | |
| Trifluoroacetic Acid SCHEMBL7414816 | 0.86 | FPR2 (0.44) | FPR2FPR1NPY1R | |
| SCHEMBL7420917 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2BFPR2FPR1NPY1R | |
| SCHEMBL7420920 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2BFPR2FPR1NPY1R | |
| Trifluoroacetic Acid SCHEMBL7422390 | 0.82 | ITGB3 (0.62) | ITGB3ITGA2BFPR2FPR1NPY1R | |
| SCHEMBL7415142 | 0.82 | ITGB3 (0.73) | ITGB3ITGA2BFPR2FPR1 | |
| Trifluoroacetic Acid SCHEMBL8121463 | 0.81 | FPR2 (0.46) | ITGB3ITGA2BFPR2FPR1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | claimed |
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | disclosed |