Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415375 | 1.00 | CTSL (0.52) | CTSLMMEECE1TACR1CTSB | |
| SCHEMBL7424510 | 0.83 | CTSL (0.48) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL7419140 | 0.83 | CTSL (0.48) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL10803689 | 0.83 | MME (0.63) | CTSLMMEECE1TACR1CTSB | |
| SCHEMBL10803697 | 0.83 | MME (0.63) | CTSLMMEECE1TACR1CTSB | |
| SCHEMBL10805328 | 0.82 | CTSL (0.59) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL10746345 | 0.81 | CAPN1 (0.61) | CTSLMMEECE1TACR1CTSB | |
| SCHEMBL10746340 | 0.81 | CAPN1 (0.61) | CTSLMMEECE1TACR1CTSB | |
| SCHEMBL7420909 | 0.81 | CTSB (0.56) | CTSLMMEECE1CTSBCTSS | |
| SCHEMBL7415829 | 0.81 | CTSB (0.56) | CTSLMMEECE1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256677-A | Enzyme inhibitor for treating acquired immune deficiency syndrome | ABBOTT LABORATORIES (US) | 1993-10-26 | — | — | US | disclosed |
| WO-1992017176-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-10-15 | — | — | WO | disclosed |
| US-5151438-A | Enzyme inhibitors for treatment of aids | ABBOTT LABORATORIES (US) | 1992-09-29 | — | — | US | disclosed |