Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424510 | 1.00 | CTSL (0.48) | CTSLCTSKCTSBCTSSCTSD | |
| SCHEMBL7420907 | 0.83 | CTSB (0.56) | CTSLCTSKCTSBCTSS | |
| SCHEMBL7414133 | 0.83 | CTSB (0.56) | CTSLCTSKCTSBCTSS | |
| SCHEMBL7415829 | 0.83 | CTSB (0.56) | CTSLCTSKCTSBCTSS | |
| SCHEMBL7420909 | 0.83 | CTSB (0.56) | CTSLCTSKCTSBCTSS | |
| SCHEMBL7415375 | 0.83 | CTSL (0.52) | CTSLCTSKCTSBCTSSTACR1 | |
| SCHEMBL7414958 | 0.83 | CTSL (0.52) | CTSLCTSKCTSBCTSSTACR1 | |
| SCHEMBL7809241 | 0.82 | CTSD (0.55) | CTSLCTSKCTSBCTSSCTSD | |
| SCHEMBL7410781 | 0.81 | CASP1 (0.52) | CTSLCTSKCTSBCTSSCTSD | |
| SCHEMBL7806366 | 0.80 | CTSL (0.47) | CTSLCTSKCTSBCTSSCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017176-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-10-15 | — | — | WO | disclosed |
| US-5151438-A | Enzyme inhibitors for treatment of aids | ABBOTT LABORATORIES (US) | 1992-09-29 | — | — | US | disclosed |