Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 7/20 | 0.56 |
| ▸ | CTSL | P07711 | 4/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420907 | 1.00 | CTSB (0.56) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL7414133 | 1.00 | CTSB (0.56) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL7415829 | 1.00 | CTSB (0.56) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL7424510 | 0.83 | CTSL (0.48) | CTSBCTSLCTSSCTSK | |
| SCHEMBL7419140 | 0.83 | CTSL (0.48) | CTSBCTSLCTSSCTSK | |
| SCHEMBL7410781 | 0.83 | CASP1 (0.52) | CTSBCTSLCTSSCTSKCASP3 | |
| SCHEMBL8769479 | 0.82 | CTSB (0.64) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL29861422 | 0.81 | CTSB (0.61) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL9579040 | 0.81 | CASP3 (0.46) | CTSBCTSLCTSSCASP3REN | |
| SCHEMBL7416124 | 0.81 | CASP3 (0.49) | CTSBCTSLCTSSCASP3REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017176-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-10-15 | — | — | WO | disclosed |
| US-5151438-A | Enzyme inhibitors for treatment of aids | ABBOTT LABORATORIES (US) | 1992-09-29 | — | — | US | disclosed |