SCHEMBL7415161

SCHEMBL7415161

CCc1cc(OCc2ccc(-c3c(Cl)c[nH]c3C#N)cc2)c2ccccc2n1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 2/20 0.53
AGTR2 P50052 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7415898 0.93 AGTR1 (0.45) AGTR1AGTR2
SCHEMBL7410622 0.89 ADAM17 (0.42) AGTR1AGTR2
SCHEMBL7419131 0.83 AGTR1 (0.53) AGTR1AGTR2
SCHEMBL7421726 0.82 KDM4C (0.38)
SCHEMBL7419130 0.81 AGTR1 (0.51) AGTR1AGTR2
SCHEMBL7419213 0.81 NR1H4 (0.44)
SCHEMBL9178138 0.78 AGTR1 (0.63) AGTR1AGTR2
SCHEMBL7417812 0.75 AGTR1 (0.52) AGTR1AGTR2
SCHEMBL7418072 0.74 AGTR1 (0.47) AGTR1AGTR2
SCHEMBL4767008 0.73 AGTR1 (0.59) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993016071-A1 HETEROCYCLIC DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-08-19 WO disclosed