Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415901 | 0.93 | BCAT2 (0.40) | AGTR1AGTR2LMNAMAPTHTT | |
| SCHEMBL7410625 | 0.89 | ADAM17 (0.42) | LMNAMAPTHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7421729 | 0.83 | RAB9A (0.39) | LMNAMAPTHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7464057 | 0.80 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9178138 | 0.74 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL7415161 | 0.74 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL4767008 | 0.73 | AGTR1 (0.59) | AGTR1AGTR2LMNAMAPTHTT | |
| SCHEMBL7467651 | 0.73 | AGTR1 (0.43) | AGTR1AGTR2LMNAMAPTHTT | |
| SCHEMBL7419130 | 0.72 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9458643 | 0.71 | AGTR1 (0.56) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016071-A1 | HETEROCYCLIC DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-19 | — | — | WO | disclosed |