Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415161 | 0.93 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL7410622 | 0.87 | ADAM17 (0.42) | AGTR1AGTR2KDM4C | |
| SCHEMBL7421726 | 0.81 | KDM4C (0.38) | KDM4C | |
| SCHEMBL7419213 | 0.79 | NR1H4 (0.44) | KDM4C | |
| SCHEMBL7419131 | 0.76 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL7415901 | 0.74 | BCAT2 (0.40) | AGTR1AGTR2KDM4CBCAT2 | |
| SCHEMBL7419130 | 0.74 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL7850138 | 0.74 | MAPT (0.46) | AGTR1AGTR2 | |
| SCHEMBL9183186 | 0.72 | KDM4E (0.57) | AGTR1AGTR2 | |
| SCHEMBL9182577 | 0.72 | KDM4E (0.56) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016071-A1 | HETEROCYCLIC DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-19 | — | — | WO | disclosed |