Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410693 | 1.00 | F2 (0.37) | F2LMNAPPM1BTSHRGAA | |
| SCHEMBL1751899 | 1.00 | F2 (0.37) | F2LMNAPPM1BTSHRGAA | |
| SCHEMBL15903870 | 0.86 | TDP1 (0.39) | GAAKMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL5692181 | 0.76 | PKM (0.35) | LMNAMAPTNPC1RAB9ACYP2C9 | |
| SCHEMBL30686187 | 0.71 | LMNA (0.38) | LMNATSHRGAAKMT2AMAPT | |
| SCHEMBL10392788 | 0.66 | LMNA (0.44) | F2LMNATSHRGAAKMT2A | |
| SCHEMBL636837 | 0.63 | LMNA (0.48) | F2LMNAPPM1BTSHRGAA | |
| SCHEMBL1751897 | 0.63 | LMNA (0.48) | F2LMNAPPM1BTSHRGAA | |
| SCHEMBL637664 | 0.63 | LMNA (0.48) | F2LMNAPPM1BTSHRGAA | |
| SCHEMBL30526381 | 0.63 | F2 (0.48) | F2LMNATSHRGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |