Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415366 | 0.81 | KDM4E (0.66) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL11521377 | 0.80 | LMNA (0.57) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL7408332 | 0.77 | HRH3 (0.51) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL9650084 | 0.77 | HTR2A (0.71) | LMNAHTR7KDM4E | |
| Hydrochloric Acid SCHEMBL7404506 | 0.76 | HRH3 (0.50) | KMT2AMEN1ALDH1A1LMNAGAA | |
| Hydrochloric Acid SCHEMBL9649714 | 0.76 | HTR2A (0.70) | LMNAHTR7KDM4EOPRM1OPRD1 | |
| SCHEMBL6211935 | 0.74 | LTA4H (0.60) | HRH2HRH1 | |
| SCHEMBL1583103 | 0.74 | KDM4E (0.69) | KDM4E | |
| SCHEMBL10692369 | 0.74 | KMT2A (0.53) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL7253842 | 0.73 | HTR2A (0.64) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |