Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | LAP3 | P28838 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.48 |
| ▸ | IL1RN | P18510 | 2/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960649 | 1.00 | LTA4H (0.67) | LTA4HESR1ESR2LAP3MIF | |
| SCHEMBL741541 | 0.86 | LTA4H (0.61) | LTA4HESR1ESR2LAP3KMT2A | |
| SCHEMBL762691 | 0.86 | LTA4H (0.61) | LTA4HESR1ESR2LAP3KMT2A | |
| SCHEMBL7961571 | 0.86 | LTA4H (0.69) | LTA4HLAP3 | |
| SCHEMBL7417389 | 0.86 | LTA4H (0.53) | LTA4HESR1ESR2LAP3TAAR1 | |
| SCHEMBL741542 | 0.86 | LTA4H (0.61) | LTA4HESR1ESR2LAP3KMT2A | |
| SCHEMBL2606756 | 0.85 | LTA4H (0.77) | LTA4HLAP3SLC7A5KMT2A | |
| SCHEMBL8174333 | 0.85 | LTA4H (0.77) | LTA4HLAP3SLC7A5KMT2A | |
| SCHEMBL6339522 | 0.85 | LTA4H (0.77) | LTA4HLAP3SLC7A5KMT2A | |
| SCHEMBL7964844 | 0.85 | LTA4H (0.77) | LTA4HLAP3SLC7A5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |