Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415569 | 0.81 | CGAS (0.45) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL7413980 | 0.81 | DRD2 (0.36) | HTR1AHTR1DHTR1B | |
| SCHEMBL7406266 | 0.75 | NR2E1 (0.55) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL7414253 | 0.74 | HTR1A (0.42) | HTR1AHTR1DHTR1B | |
| SCHEMBL7979065 | 0.72 | HTR1A (0.48) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL7410637 | 0.71 | MTNR1A (0.53) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL7111545 | 0.70 | MTNR1A (0.57) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL11423778 | 0.69 | HTR1A (0.45) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL11284150 | 0.68 | RB1 (0.64) | MTNR1AMTNR1B | |
| SCHEMBL16026808 | 0.68 | SIRT1 (0.54) | HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | claimed |
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |