Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.45 |
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422355 | 0.91 | AAK1 (0.44) | CTSKCTSLHSD17B10MAPTNPSR1 | |
| SCHEMBL7429552 | 0.91 | HSD17B10 (0.45) | CTSKCTSLHSD17B10MAPTNPSR1 | |
| SCHEMBL7420936 | 0.89 | CTSL (0.41) | CTSKCTSLHSD17B10MAPTNPSR1 | |
| SCHEMBL7426033 | 0.87 | MAPT (0.42) | CTSKCTSLHSD17B10MAPTNPSR1 | |
| SCHEMBL7421323 | 0.85 | NTSR1 (0.44) | CTSKCTSLHSD17B10MAPTNPSR1 | |
| SCHEMBL27300721 | 0.81 | HSD17B10 (0.48) | CTSKCTSLHSD17B10MAPTNPSR1 | |
| SCHEMBL5869698 | 0.80 | CTSK (0.52) | CTSKCTSLHSD17B10CTSBATM | |
| SCHEMBL5869701 | 0.80 | CTSK (0.52) | CTSKCTSLHSD17B10CTSBATM | |
| SCHEMBL5869693 | 0.80 | CTSK (0.52) | CTSKCTSLHSD17B10CTSBATM | |
| SCHEMBL7418972 | 0.79 | CTSK (0.43) | CTSKCTSLMAPTNPSR1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |