Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 3/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13293358 | 0.86 | ITGB3 (0.61) | ITGB3ITGA2BGAAFAAHHRH2 | |
| SCHEMBL7422613 | 0.84 | ALDH1A1 (0.65) | ITGB3ITGA2BLMNAALDH1A1GAA | |
| SCHEMBL13577671 | 0.82 | GAA (0.65) | LMNAALDH1A1GAAFAAHHRH2 | |
| SCHEMBL7425219 | 0.80 | SIGMAR1 (0.52) | LMNAALDH1A1GAASIGMAR1FAAH | |
| SCHEMBL7425223 | 0.80 | SIGMAR1 (0.52) | LMNAALDH1A1GAASIGMAR1FAAH | |
| SCHEMBL23419791 | 0.80 | SMN1; SMN2 (0.65) | ALDH1A1GAAFAAHNPC1RAB9A | |
| SCHEMBL3037921 | 0.80 | HRH3 (0.65) | ITGB3ITGA2BALDH1A1FAAHKDM4E | |
| SCHEMBL18177893 | 0.79 | ALDH1A1 (0.78) | LMNAALDH1A1GAASIGMAR1FAAH | |
| SCHEMBL10222154 | 0.79 | MC4R (0.60) | ITGB3ITGA2BLMNAALDH1A1SIGMAR1 | |
| SCHEMBL15858108 | 0.79 | MC4R (0.60) | LMNAALDH1A1SIGMAR1MC4RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |