Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.50 |
| ▸ | VNN1 | O95497 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059851 | 0.94 | AKR1C1 (0.53) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL7413719 | 0.86 | F7 (0.47) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL7412060 | 0.82 | MAPT (0.55) | ALDH1A1LMNAKMT2A | |
| SCHEMBL7418588 | 0.78 | PLOD2 (0.44) | ALDH1A1LMNAPLOD2HDAC1KMT2A | |
| SCHEMBL4825571 | 0.76 | AKR1C1 (0.53) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Hydrochloric Acid SCHEMBL23778493 | 0.75 | AKR1C1 (0.52) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL4656479 | 0.74 | AKR1C1 (0.66) | ALDH1A1LMNAHDAC1KMT2AAKR1C1 | |
| SCHEMBL2702767 | 0.74 | LMNA (0.64) | ALDH1A1LMNACYP3A4KMT2ATDP1 | |
| Niacin SCHEMBL28548184 | 0.73 | — | — | |
| SCHEMBL13070336 | 0.71 | CES2 (0.50) | ALDH1A1LMNACYP1A2HDAC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152866-C | Benzimidazoles, production thereof and use thereof medicaments | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-06-09 | — | — | CN | disclosed |
| EP-1095025-B1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-12-11 | — | — | EP | disclosed |
| CN-1308614-A | Benzimidazoles, production thereof and use thereof medicaments | BOEHRINGER INGELHEIM PHAMA KG (DE) | 2001-08-15 | — | — | CN | disclosed |
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |