Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10148114 | 0.86 | GABRA1 (0.47) | MTNR1ATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4826400 | 0.83 | LMNA (0.44) | MTNR1ATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL394419 | 0.83 | TAAR1 (0.58) | TAAR1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL18462466 | 0.83 | TAAR1 (0.42) | MTNR1ATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4208995 | 0.82 | KDM4C (0.40) | MTNR1ATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2168952 | 0.80 | EED (0.46) | MTNR1ALMNAEEDAOC3KDM4C | |
| SCHEMBL2602430 | 0.80 | EED (0.46) | MTNR1AEEDKDM4CHTR2AHTR2C | |
| SCHEMBL29791651 | 0.80 | EED (0.46) | MTNR1ALMNAEEDAOC3KDM4C | |
| SCHEMBL7377233 | 0.77 | KDM4C (0.47) | MTNR1ALMNAEEDKDM4CFAAH | |
| SCHEMBL14518837 | 0.76 | MTNR1A (0.46) | MTNR1ALMNAEEDKDM4CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027332-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999018074-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Britol-Myers Squibb Pharma Company (US) | 1999-04-15 | — | — | WO | disclosed |