Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416858 | 0.83 | DPP4 (0.33) | TNKSTNKS2F10 | |
| SCHEMBL7423394 | 0.83 | DPP4 (0.33) | TNKSTNKS2F10 | |
| SCHEMBL8040065 | 0.78 | TNKS (0.43) | SIRT2SIRT1TNKSTNKS2 | |
| SCHEMBL7424934 | 0.78 | FNTA (0.44) | — | |
| SCHEMBL7417088 | 0.77 | CHRNB2 (0.34) | SIRT2SIRT1TNKSTNKS2F10 | |
| SCHEMBL7419118 | 0.76 | SIRT2 (0.55) | SIRT2SIRT1HRH3 | |
| SCHEMBL7426687 | 0.76 | SIRT2 (0.55) | SIRT2SIRT1HRH3 | |
| SCHEMBL8833260 | 0.76 | SIRT2 (0.55) | SIRT2SIRT1HRH3 | |
| SCHEMBL7416241 | 0.76 | TRPA1 (0.35) | SIRT2SIRT1TNKSTNKS2F10 | |
| SCHEMBL7418472 | 0.74 | PRMT5 (0.43) | SIRT2SIRT1TNKSTNKS2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-A4 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0853618-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1998-07-22 | — | — | EP | disclosed |
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |