SCHEMBL7417159

SCHEMBL7417159

CCCCCCC[C@H](CC(=O)OC(C)(C)C)C(=O)N[C@H]1Cc2ccccc2N(OC)C1=O

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 3/20 0.44
MMP3 P08254 3/20 0.44
MME P08473 1/20 0.38
ACE P12821 1/20 0.38
SCN9A Q15858 3/20 0.38
REN P00797 3/20 0.37
CCKBR P32239 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9199359 0.79 MMP1 (0.35) MMP1MMP3ACERENCCKBR
SCHEMBL7416242 0.75 SCN9A (0.40) ACESCN9AREN
SCHEMBL9288876 0.73 MMP1 (0.54) MMP1MMP3MMEACE
SCHEMBL4799807 0.73 MTNR1A (0.49) MMEACE
SCHEMBL4799822 0.73 MTNR1A (0.49) MMEACE
SCHEMBL4800991 0.72 PYGL (0.43)
SCHEMBL14193208 0.72 PYGL (0.43)
SCHEMBL4800980 0.72 PYGL (0.43)
SCHEMBL7416568 0.70 SCN9A (0.43) ACESCN9A
SCHEMBL14193205 0.67 SLC6A2 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994021612-A1 CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-09-29 WO disclosed