Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417159 | 0.79 | MMP1 (0.44) | MMP1MMP3RENACECCKBR | |
| SCHEMBL9196774 | 0.70 | EPHX2 (0.42) | ACECCKBR | |
| SCHEMBL6159696 | 0.64 | L3MBTL1 (0.44) | MMP1MMP3CTSKL3MBTL1BIRC2 | |
| SCHEMBL6294116 | 0.64 | MMP2 (0.62) | MMP1MMP3ACEBIRC2MMP2 | |
| SCHEMBL8055025 | 0.64 | MMP2 (0.77) | MMP1MMP3MMP2 | |
| SCHEMBL8221385 | 0.64 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL8221381 | 0.64 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL8218720 | 0.64 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL8218717 | 0.64 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL8218572 | 0.64 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |