Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 2/20 | 0.51 |
| ▸ | MME | P08473 | 2/20 | 0.50 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.45 |
| ▸ | TPH1 | P17752 | 2/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | GNA15 | P30679 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411122 | 0.85 | ALDH1A1 (0.52) | MME | |
| SCHEMBL7411480 | 0.78 | PDCD1 (0.40) | POLBKMT2A | |
| SCHEMBL7417513 | 0.78 | PPARG (0.55) | MME | |
| SCHEMBL7417475 | 0.77 | MME (0.53) | MMESLC13A5MAOBFFAR1PTGDR | |
| SCHEMBL7417467 | 0.77 | MME (0.53) | MMESLC13A5MAOBFFAR1PTGDR | |
| SCHEMBL7409300 | 0.77 | LDHA (0.44) | — | |
| SCHEMBL7361415 | 0.77 | CYP1A2 (0.47) | — | |
| SCHEMBL7361412 | 0.77 | CYP1A2 (0.47) | — | |
| SCHEMBL7345126 | 0.77 | TPH1 (0.63) | HSD17B2MMESLC13A5MAOBFFAR1 | |
| SCHEMBL7345132 | 0.77 | TPH1 (0.63) | HSD17B2MMESLC13A5MAOBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660840-B1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996026729-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES AS ECE INHIBITORS | CIBA-GEIGY AG (CH) | 1996-09-06 | — | — | WO | disclosed |
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| US-5250522-A | Neutral endopeptidase inhibitors; cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |