Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | C1R | P00736 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18585567 | 0.81 | KDM4E (0.50) | KCNH2GRM5GRM2KMT2ABACE1 | |
| SCHEMBL7666919 | 0.78 | MYC (0.44) | KCNH2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL3085385 | 0.78 | CYP1A2 (0.58) | KMT2ABACE1KDM4EALDH1A1HPGD | |
| SCHEMBL7024735 | 0.76 | ACACA (0.46) | GRM2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL1257332 | 0.74 | BACE1 (0.44) | KCNH2GRM2KMT2AC1RBACE1 | |
| SCHEMBL7259981 | 0.74 | ACHE (0.47) | KCNH2KMT2ABACE1KDM4EALDH1A1 | |
| SCHEMBL29726892 | 0.74 | BACE1 (0.44) | KCNH2GRM2KMT2AC1RBACE1 | |
| SCHEMBL5679983 | 0.74 | ALOX15 (0.58) | KCNH2GRM5KMT2AC1RKDM4E | |
| SCHEMBL7417644 | 0.72 | KDM4E (0.45) | KCNH2GRM2KMT2AC1RBACE1 | |
| SCHEMBL25330955 | 0.71 | NQO2 (0.43) | KCNH2GRM2KMT2ABACE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |