Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415367 | 0.91 | DRD2 (0.36) | KDM4EDRD2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7426602 | 0.85 | ALDH1A1 (0.40) | HTR1AADRA2ASLC6A2SLC6A4CXCR5 | |
| SCHEMBL7325790 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL7425334 | 0.69 | AKR1C3 (0.37) | KDM4EALDH1A1MAPTHPGDHTT | |
| SCHEMBL7326938 | 0.65 | NR4A1 (0.36) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL25509092 | 0.64 | TRPV1 (0.42) | ALDH1A1 | |
| SCHEMBL7332416 | 0.64 | ALDH1A1 (0.38) | KDM4EALDH1A1MAPTHPGDHTT | |
| SCHEMBL8581327 | 0.64 | HTR1A (0.41) | HTR1AADRA2ASLC6A2SLC6A4KDM4E | |
| SCHEMBL7526110 | 0.64 | BCL2L1 (0.48) | HTR1AADRA2ASLC6A2SLC6A4KDM4E | |
| SCHEMBL7331313 | 0.63 | PARP1 (0.51) | KDM4EALDH1A1MAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016072-A1 | BENZOPYRAN, BENZOTHIOPYRAN AND BENZOFURAN DERIVATIVES AS 5-HT4 ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-19 | — | — | WO | disclosed |