Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412531 | 0.94 | DRD2 (0.47) | HTR1ADRD2HTR7HTR6SLC6A3 | |
| SCHEMBL7410875 | 0.88 | DRD2 (0.50) | HRH3HTR1ADRD2HTR7HRH2 | |
| Hydrochloric Acid SCHEMBL7413705 | 0.86 | DRD2 (0.48) | HTR1ADRD2HTR7SLC6A3HTR2A | |
| Hydrochloric Acid SCHEMBL7413702 | 0.86 | DRD2 (0.48) | HTR1ADRD2HTR7SLC6A3HTR2A | |
| SCHEMBL7409358 | 0.82 | EPHX2 (0.41) | HRH3HTR1ADRD2HTR7HTR6 | |
| SCHEMBL7414683 | 0.82 | SLC6A3 (0.46) | HRH3HTR1ADRD2HTR7HRH2 | |
| SCHEMBL7415382 | 0.80 | DRD2 (0.47) | HTR1ADRD2HTR7SLC6A3HTR2A | |
| SCHEMBL7404666 | 0.79 | SLC6A3 (0.47) | HRH3HTR1ADRD2HTR7HTR6 | |
| SCHEMBL7407159 | 0.79 | DRD2 (0.47) | HTR1ADRD2HTR7SLC6A3HTR2A | |
| SCHEMBL7416352 | 0.79 | SLC6A3 (0.45) | HRH3HTR1ADRD2HRH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |