Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443421 | 0.87 | NPC1 (0.40) | ALDH1A1HPGDKMT2AMEN1LTA4H | |
| SCHEMBL7434422 | 0.87 | ALDH1A1 (0.39) | ALDH1A1HPGDKMT2AMEN1LTA4H | |
| SCHEMBL7359248 | 0.87 | ALDH1A1 (0.39) | ALDH1A1HPGDKMT2AMEN1LTA4H | |
| SCHEMBL7422678 | 0.86 | ALDH1A1 (0.38) | ALDH1A1HPGDKMT2AMEN1LTA4H | |
| SCHEMBL7420793 | 0.84 | ALDH1A1 (0.36) | ALDH1A1HPGDKMT2AMEN1LTA4H | |
| SCHEMBL7448927 | 0.79 | DRD2 (0.40) | ALDH1A1HPGDKMT2AMEN1LTA4H | |
| SCHEMBL3133531 | 0.78 | DPP4 (0.38) | ALDH1A1RAB9ANPC1SMN1; SMN2CYP2C19 | |
| SCHEMBL7426597 | 0.76 | DRD2 (0.39) | ALDH1A1HPGDKMT2AMEN1LTA4H | |
| SCHEMBL6052882 | 0.76 | SCN3A (0.41) | ALDH1A1KCNH2 | |
| SCHEMBL6165827 | 0.75 | LMNA (0.42) | KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |