Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434422 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MEN1HPGDKMT2AUBE2T | |
| SCHEMBL7443421 | 0.93 | NPC1 (0.40) | ALDH1A1MEN1HPGDKMT2AF2 | |
| SCHEMBL7422678 | 0.92 | ALDH1A1 (0.38) | ALDH1A1MEN1HPGDKMT2AUBE2T | |
| SCHEMBL7418317 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MEN1HPGDKMT2AUBE2T | |
| SCHEMBL7420793 | 0.82 | ALDH1A1 (0.36) | ALDH1A1MEN1HPGDKMT2ALTA4H | |
| SCHEMBL7448927 | 0.81 | DRD2 (0.40) | ALDH1A1MEN1HPGDKMT2AUBE2T | |
| SCHEMBL7361665 | 0.80 | GAA (0.36) | SMN1; SMN2CYP2C19 | |
| SCHEMBL7479291 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MEN1HPGDKMT2AF2 | |
| SCHEMBL7418301 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MEN1HPGDKMT2AUBE2T | |
| SCHEMBL7367539 | 0.75 | DPP4 (0.33) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |