Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421747 | 0.86 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7416761 | 0.84 | POLB (0.41) | L3MBTL1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL5638613 | 0.81 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7423982 | 0.79 | NOTUM (0.47) | L3MBTL1POLBLMNA | |
| SCHEMBL7420002 | 0.78 | POLB (0.40) | L3MBTL1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7414937 | 0.76 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7795540 | 0.75 | L3MBTL1 (0.44) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL9196586 | 0.71 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4413239 | 0.70 | NOTUM (0.47) | L3MBTL1MEN1KMT2ANR1I3 | |
| SCHEMBL7423680 | 0.70 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1GAAPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |