Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR1I3 | Q14994 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5638613 | 0.92 | L3MBTL1 (0.49) | L3MBTL1NR1I3POLBCTSKKMT2A | |
| SCHEMBL4413239 | 0.85 | NOTUM (0.47) | L3MBTL1NR1I3KMT2AMEN1SCN9A | |
| SCHEMBL31160375 | 0.82 | NFKB1 (0.38) | L3MBTL1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL10691716 | 0.81 | AVPR2 (0.45) | L3MBTL1POLBTHRB | |
| SCHEMBL4420583 | 0.79 | CASP6 (0.40) | NR1I3KMT2AMEN1SCN9ANOTUM | |
| SCHEMBL8764748 | 0.78 | MAPK1 (0.42) | NR1I3KMT2AMEN1SCN9ALIPE | |
| SCHEMBL29986227 | 0.76 | DRD2 (0.47) | NR1I3CTSKKMT2AMEN1SCN9A | |
| SCHEMBL7421747 | 0.76 | L3MBTL1 (0.41) | L3MBTL1NR1I3POLBKMT2AMEN1 | |
| SCHEMBL30987423 | 0.76 | DRD2 (0.52) | POLBTHRB | |
| SCHEMBL7416761 | 0.76 | POLB (0.41) | L3MBTL1POLBKMT2AMEN1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | disclosed |