Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416761 | 0.85 | POLB (0.41) | POLBL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL7414937 | 0.85 | L3MBTL1 (0.42) | POLBL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL7423982 | 0.84 | NOTUM (0.47) | POLBL3MBTL1NPC1RAB9APTGER1 | |
| SCHEMBL7423680 | 0.81 | L3MBTL1 (0.52) | POLBL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL5638613 | 0.81 | L3MBTL1 (0.49) | POLBL3MBTL1ALDH1A1GAASCN9A | |
| SCHEMBL9196586 | 0.80 | L3MBTL1 (0.39) | POLBL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL7421747 | 0.79 | L3MBTL1 (0.41) | POLBL3MBTL1ALDH1A1GAAMEN1 | |
| SCHEMBL7418469 | 0.78 | L3MBTL1 (0.40) | POLBL3MBTL1ALDH1A1GAAMEN1 | |
| SCHEMBL7795540 | 0.74 | L3MBTL1 (0.44) | POLBL3MBTL1NPC1SCN9AMEN1 | |
| SCHEMBL4413239 | 0.70 | NOTUM (0.47) | L3MBTL1SCN9AMEN1KMT2ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |