SCHEMBL2640244

SCHEMBL2640244

NC1CCC(C[C@H](N)[C]=O)CC1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 1/20 0.36
ANPEP P15144 2/20 0.32
ENPEP Q07075 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943205 1.00 CPB2 (0.36) CPB2ANPEPENPEP
SCHEMBL7608856 0.91
SCHEMBL7375837 0.82
SCHEMBL7375737 0.82 ALOX5 (0.34)
SCHEMBL5665177 0.81 ANPEP (0.34) ANPEPENPEP
SCHEMBL8190656 0.81 ANPEP (0.34) ANPEPENPEP
SCHEMBL1449256 0.80 METAP1 (0.37)
SCHEMBL7418539 0.80 METAP1 (0.37)
SCHEMBL3504941 0.80 METAP1 (0.37)
SCHEMBL10583764 0.77 CPN1 (0.42) CPB2ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673254-A4 6-POSITION MODIFIED DECAPEPTIDE LHRH ANTAGONISTS. ABBOTT LAB (US) 1998-11-18 EP claimed
US-5698522-A INHIBIT RELEASE OF LUTEINIZING HORMONE RELEASING HORMONE ABBOTT LABORATORIES (US) 1997-12-16 US claimed
JP-H08504209-A 1996-05-07 JP claimed
EP-0673254-A1 6-POSITION MODIFIED DECAPEPTIDE LHRH ANTAGONISTS ABBOTT LABORATORIES (US) 1995-09-27 EP claimed
WO-1994013313-A1 6-POSITION MODIFIED DECAPEPTIDE LHRH ANTAGONISTS ABBOTT LABORATORIES (US) 1994-06-23 WO claimed
EP-0673254-A4 6-POSITION MODIFIED DECAPEPTIDE LHRH ANTAGONISTS. ABBOTT LAB (US) 1998-11-18 EP disclosed
US-5698522-A INHIBIT RELEASE OF LUTEINIZING HORMONE RELEASING HORMONE ABBOTT LABORATORIES (US) 1997-12-16 US disclosed
EP-0673254-A1 6-POSITION MODIFIED DECAPEPTIDE LHRH ANTAGONISTS ABBOTT LABORATORIES (US) 1995-09-27 EP disclosed
WO-1994013313-A1 6-POSITION MODIFIED DECAPEPTIDE LHRH ANTAGONISTS ABBOTT LABORATORIES (US) 1994-06-23 WO disclosed