Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 17/20 | 0.50 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476111 | 0.91 | SLC22A12 (0.40) | SLC22A12 | |
| SCHEMBL7427533 | 0.90 | ALOX5AP (0.46) | SLC22A12 | |
| SCHEMBL7466262 | 0.89 | S1PR3 (0.41) | SLC22A12RORC | |
| SCHEMBL7707842 | 0.89 | ALOX5AP (0.45) | SLC22A12 | |
| SCHEMBL7418814 | 0.85 | OXER1 (0.41) | SLC22A12OXER1 | |
| SCHEMBL7425218 | 0.83 | MEN1 (0.42) | — | |
| SCHEMBL7707845 | 0.83 | SLC22A12 (0.37) | SLC22A12OXER1 | |
| SCHEMBL7427469 | 0.83 | AGTR1 (0.40) | SLC22A12OXER1 | |
| SCHEMBL7425988 | 0.83 | AGTR1 (0.36) | SLC22A12OXER1 | |
| SCHEMBL7424763 | 0.83 | AGTR1 (0.39) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820441-B1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6069156-A | Indole derivatives as cGMP-PDE inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-30 | — | — | US | disclosed |
| WO-1996032379-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-17 | — | — | WO | disclosed |